Cotinine (Nicotine Metabolite) Detection
Cotinine is the predominant metabolite of nicotine and used as a biomarker for exposure to tobacco smoke. In the human body, cotinine has a half-life of 20 hours and can be detected up to a week after the use of tobacco.
The level of cotinine in the saliva, urine and blood is proportionate to the amount of exposure to tobacco smoke, including secondary (passive) smoke making cotinine a valuable indicator of tobacco smoke exposure.
In urine, values between 11ng/mL and 30ng/mL is associated with light smoking or passive smoking exposure. Levels in active smokers typically reach 500ng/mL or more.
In saliva, values between 1ng/mL and 30ng/mL is associated with light smoking or passive smoking exposure. Levels in active smokers typically reach 100ng/mL or more.
RM28/Test